Sunday, 14th July RACI Biomolecular Division Conference 2013

• Diversity-oriented synthesis for oncology drug discovery - Lisa A Marcaurelle
• Discovery of New Treatments for Acute Myeloid Leukaemia - Christopher J Burns
• Discovery, structure-guided design and validation of WEHI-539, a novel, potent and selective inhibitor of the pro-survival BCL-2 family member BCL-X_L - Guillaume Lessene

Dinner provided at the conference venue.

Drinks provided

• The influence of ionic liquids on the Knoevenagel condensation of pyrrole with phenyl acetonitriles - Ahmed Abdullah Alotaibi
• The Sulfonadyns: a new class of GTP-competitive dynamin  inhibitor and anti-epileptic compound  - Joseph I Ambrus
• Virtual screening for novel modulators at alternative nachr subunit interfaces - Thomas Balle
• Breaking Bad: The Clandestine Rational Design of Cannabimimetic Indoles as Drugs of Abuse - Samuel D Banister
• The Design and Synthesis of Selective α7 nAChR Agonists - Corinne Beinat
• An in-silico directed investigation of novel diterpenoid compounds as potential substrates of opioid receptors - Matthew Bendikov
• Design and synthesis of “clickable” glycosyl-amino acids.  - Consulato Cara
• Hit-to-Lead Analoguing of CID1867212 for the development of a treatment for Chagas Disease - Jason H Chaplin
• The Use of Soluble Protein Structures in Modelling Helical Proteins in a Layered Membrane - William B Church
• Preparation and evaluation of peptidomimetic scaffold targeting MCL-1 - Jean-Marc Garnier
• Synthesis and Biological Evaluation of Glycopeptide Cancer Vaccine Candidates - Leo Corcilius
• Application of flow hydrogenation to medicinal chemistry - Peter Cossar
• Using a target-based assay for screening of lead-like enhanced natural product extracts against tuberculosis enzymes - Yousef Dashti
• Oxidant scavenging by selenium and sulfur compounds: absolute rate constants and assessment of biological relevance - Michael J Davies
• Synthesis and Evaluation of Gallinamide A Analogues as Antimalarial Drug Leads - Nabiha T. Elias
• The design of small molecule inhibitors of Plasmepsin V for intervention against malaria - Michelle Gazdik
• 'Cell-Surface Sialic Acids: Potential Targets for the Development of Anti-Cancer Therapeutics' - Darren Grice
• Multi-dimensional immobilised metal affinity chromatography: Optimising the capture of multiple metabolites from a single bacterial culture - Jiesi Gu
• Iron promoted Allylic Amination of Unactivated Alkenes  - Ayesha Hussain
• Synthesis of water soluble mono and bis[60]fullerene based di and tetra cationic peptoids as potential anti-infective agents - Sreenu Jennepalli
• A novel and versatile synthesis of pseudaminic acid analogues - Milton J Kiefel
• Queensland Compound Library (QCL) – Australia’s National small molecule diversity resource - Mikhail Krasavin
• Synthesis of forward and retro ferrioxamine E via metal templation - Tulip Lifa
• An expedient and robust synthesis of solid-supported chemical biology probes - Andrew J.S. Lin
• Synthesis and HIV Inhibitory Activity of N-terminal Chemokine Receptor Sulfopeptides - Xuyu Liu
• Design and Synthesis of Derivatives of the Marine Bioluminescent Substrate Coelenterazine - Yueting Lu
• Novel Sigma Receptor Ligands - Madhura Manohar
• Synthesis of Thioridazine-VLA-4 Antagonist Hybrids as Multi-Action Agents for Treating Haematological Malignancies - Alex Martyn
• Structural Chemistry Studies of Partial Agonists at ρ GABAC Ion Channel Receptors - Moawiah M Naffaa
• Molecular Modeling of Calpain Inhibitors - Steven Nguyen
• Boron Templated Triazole Formation - Brighid B Pappin
• Malaria - The Drug Stress Response and Development of New Actives - Chris Parkinson
• The nitroxide TEMPO is an efficient scavenger of protein-derived radicals: cellular and kinetic studies - David I Pattison
• Design and synthesis of a novel series of FLT3 inhibitors for treatment of acute myeloid leukaemia - Louisa J Phillipson
• Ellipticine and Analogues by Flow Chemistry - Cecilia C Russell
• Total Synthesis of Polydiscamide B-D and Microspinosamide - Gajan Santhakumar
• Solution structures of the DNA complexes of cytotoxic bis(phenazine-1-carboxamides) - Andre Serobian
• Novel classes of iminosugars as broad-spectrum antiviral agents - Michela Simone
• Quinazoline Sulfonamides as Dual Binders of the Proteins Bcl-2 and Bcl-xL with Potent Pro-apoptotic Cell-Based Activity - Brad E Sleebs
• The Design of Inhibitors of the Kynurenine Aminotransferases: the Enabling Tools. - Guanchen Sun
• Synthesis of novel porphyrins that are designed to be biocompatible - Fargol Taba
• 2-N-Acyl-4-cyanopyrroles as Inhibitors of the IMP-1 Metallo-β-lactamase (MBL) - Daniel T. C. Tan
• Inhibiting MAPK-activated kinase 2 to target inflammation and proliferation of glioblastoma cells - Melissa Tang
• Development of Pyrrolopyrimidines as Kinase Inhibitors - Veronica Tecchio
• The Bifurcation of Desferrioxamine B for Increasing Molecular Diversity of Iron Chelators - Thomas Telfer
• Insights into the importance of DFD-motif and insertion I1 in stabilizing the DFD-out conformation of Mnk2 kinase  - Theodosia Teo
• Development of Small Molecule Chemical Tools for Labelling Carbonic Anhydrase IX in Tumour Hypoxia - Kanae Teruya
• Isolation of Aplysamine 7, a New Bromotyrosine from the Sponge Pseudoceratina verrucosa and Determination of Its Absolute Configuration by Total Synthesis - Trong D. Tran
• Structure-based design of a-helical mimetic inhibitors of pro‑survival Bcl-2 proteins - Amelia Vom
• Efficacy of p38 MAPK inhibitors in inflammation-associated invasiveness of glioblastoma cells - Yiu To Yeung
• A heat shock protein 90 inhibitor that modulates tetratricopeptide repeat containing proteins without inducing the heat shock response - Jeanette McConnell
• Design, synthesis and characterisation of novel cathepsin and α-chymotrypsin inhibitors. - Xiaozhou Zhang
• Synthesis of norbornane-peptide hybrids as potential antibiotics - Shane Hickey
• Access to a novel class of anti-tumour mutual prodrugs - Nicholas Kirk
• Hsp70/Hsp90 Dual Inhibition Study in Colon Cancer Treatment - Yao Wang
• Dimerization of Sansalvamide A inhibits the dimer protein: Heat Shock Protein 90 - Hendra Wahyudi
• Phytochemical analysis of Withaferin-A concentration in Withania somnifera plants collected from different geographical regions of India - Leena Johny
• Variation in Rosmarinic acid content and Morphology in Ocimum basilicum [Sweet basil] cultivars - Shivani Srivastava